Human Growth Factors & Cytokines
Recombinant Human AITRL (TNFSF18)





 





		Synonyms :
Activation-induced TNFR member Ligand, TNFSF18



		Description :
AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor.  AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells.  The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain.  Recombinant human soluble AITRL is a 14.3 kDa protein, containing 126 amino acid residues corresponding to the extracellular domain of AITRL.



		Catalog #:
310-22



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability to stimulate IL-8 production by human PBMC using a concentration range of 1.0-10.0 ng/ml.  Note:  Results may vary with PBMC donors.



                AA Sequence :
ETAKEPCMAK FGPLPSKWQM ASSEPPCVNK VSDWKLEILQ NGLYLIYGQV APNANYNDVA PFEVRLYKNK DMIQTLTNKS KIQNVGGTYE LHVGDTIDLI FNSEHQVLKN NTYWGIILLA NPQFI 



		PubMed Link :
AITRL+OR+GITRL+OR+TNFSF18


Country of Origin :
USA
















        Size A
5μg
$80 
 


 



        Size B
20μg
$195 
 


 



        Size C
1mg
$5200 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.